Opportunity
The Competition
There is no effective drug available with the dual effect of both antibacterial and anti-inflammatory. The benchmark treatment options are antibiotics and topical treatments based on anti-infective components (iodine, silver, PHMB). Each of these treatments have built-in risks, either for the patient, the environment or both. A peptide such as TCP-25, identical to the ones in the body’s own defence system is very likely to neither cause bacterial resistance nor have any negative side effects for the patient or the environment.
Anti-infective | Broad spectrum | Anti-inflammatory | Anti-coagulative | Endotoxin blocking | Risks | ||
Antibiotics | Yes | No | No | No | No | Resistance development Toxicity (some) | |
Antiseptics | Silver | Yes | Yes | No | No | No | Toxicity Environmentally harmful |
PHMB | Yes | Yes | No | No | No | Carcinogenic | |
Triclosan | Yes | Yes | No | No | No | Toxic and Carcinogenic Hormone-disturbing Environmentally Harmful |
|
TCP-25 | Yes | Yes | Yes | Yes | Yes | Low |
Anti-infective | Broad spectrum | Anti-inflammatory | Anti-coagulative | Endotoxin blocking | Risks | ||
Antibiotics | Yes | No | No | No | No | Resistance development Toxicity (some) | |
Antiseptics | Silver | Yes | Yes | No | No | No | Toxicity Environmentally harmful |
PHMB | Yes | Yes | No | No | No | Carcinogenic | |
Triclosan | Yes | Yes | No | No | No | Toxic and Carcinogenic Hormone-disturbing Environmentally Harmful |
|
TCP-25 | Yes | Yes | Yes | Yes | Yes | Low |
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