The Modes of action

A. Inflammation reduction

BioC binds specifically to and neutralizes lipopolysaccharide (LPS) and related microbial products (such as LTA, peptidoglycan, lipid A), resulting primarily in reduction of the strong inflammatory effect caused by LPS and other toxins.

Upon microbial interaction, BioC forms a C-shaped structure which blocks the LPS-binding site of CD14, preventing dimerization of toll-like receptors (TLR) and inflammatory signalling. This leads to regulation of excessive levels of TNF, IL-8 and particularly IL-1ß in contaminated/infected wounds, thus promoting normal healing.

B. Infection prevention

BioC has a direct bactericidal effect caused by electrostatically binding to the bacterial cell wall and inducing lysis and bacterial death.

Furthermore, since BioC does not interfere with bacterial phagocytosis, it’s usage leads to retained phagocytic clearance and reduced bacteria-induced inflammation.